Topical Mastic Oil for Treatment of Functional Dyspepsia: A Randomized Triple-Blind Controlled Trial

Background: The main goal of the present study was to evaluate effect topical mastic oil, compared placebo on treatment functional dyspepsia (FD). Materials and Methods: Sixty-three patients with FD were included. Thirty-two subjects received oil (10 drops/TDS after meal) massage 31 sesame massage. Both groups pantoprazole (40 mg daily) along severity early satiation, postprandial fullness, epigastric pain burning assessed 4 weeks using Visual Analogue Scale (VAS) as well frequency symptoms. Satisfaction also a researcher-made questionnaire. Changes in symptoms evaluated by Friedman’s test. Results: Mean standard deviation age equal 36.95±13.64 50 (79.4%) female. experienced significant decrease all four (P<0.001). percentage satiation significantly higher group than control (76.03±34.91% vs. 37.24±38.86%, P=0.003). No differences found between (P=0.05, 0.06, 0.13, respectively). decreased similarly both groups. reported be (P=0.01). There no intolerable side effects Conclusion: Mastic reduced better placebo. In addition, satisfaction group. [GMJ.2021;10:e1965]